I wouldn't do it. A database server consumes a lot of resources and trying to run two of them on the same machine is likely to cause you some heartburn. Furthermore, configuring the hardware and software such that it will run efficiently for both Oracle and DB2 will likely be quite a challenge.
And if you have a hardware problem that will bring down both servers - something that might be avoided if you used separate servers for each.
That being said, it should be possible to run both on the same server... it just isn't wise in my opinion.
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